q 22- acrodermatitis enteropathica is due to the deficiency of (dermatology,fmge march 2012)
a.manganese
b.iron
c.zinc
d.molybdenum
ans:zinc
Acrodermatitis enteropathica (AE) is an inborn error of zinc metabolism that is inherited as an autosomal recessive disorder. Symptoms in infancy typically include periorificial and acral dermatitis , diarrhea, behavioral changes, and neurologic disturbances. In older children, failure to thrive, anorexia, alopecia, nail dystrophy, and repeated infections are most common.
Zinc deficiency may be due to inadequate intake, malabsorption, excessive loss, or a combination of these factors. If treated early, most of the symptoms are reversible and usually cause no sequelae.
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