Which of the follwing drugs is known to cause granuloma in the liver

Which of the follwing drugs is known to cause granuloma in the liver ?

a) Allopurinol
b) Nifedipine 
c) Tetracycline
d) Methyl testosterone

Answer 1

Sarcoidosis is the most important noninfectious cause; liver involvement occurs in about 2/3 of patients with sarcoidosis and occasionally is the dominant clinical manifestation. Various drugs can be responsible (eg, quinidine, sulfonamides, allopurinol, phenylbutazone). Hepatic granulomas can also occur in polymyalgia rheumatica and other collagen vascular diseases; in Hodgkin's disease, sometimes without other morphologic evidence of the lymphoma; and in many other systemic conditions.