SVC syndrome is most commonly associated with : fmge september2009

SVC syndrome is most commonly associated with :  fmge september 2009

a.  Mediastinal fibrosis

b.  Lymphoma

c.  Lung cancer

d. TB mediastinitis

answer:c 

Superior vena cava syndrome (SVCS), or superior vena cava obstruction (SVCO), is usually the result of the direct obstruction of the superior vena cava by malignancies such as compression of the vessel wall by right upper lobe tumors orthymoma and/or mediastinal lymphadenopathy. The most common malignancies that cause SVCS is bronchogenic carcinoma.

Approximately 90% of cases are associated with a cancerous tumor that is compressing the superior vena cava, such as bronchogenic carcinoma including small cell and non-small cell lung carcinoma, Burkitt lymphoma, lymphoblastic lymphomas, pre-T-cell lineage acute lymphoblastic leukemia (rare), and other acute leukemias. Syphilis and tuberculosis have also been known to cause superior vena cava syndrome SVCS can be caused by invasion or compression by a pathological process or by thrombosis in the vein itself, although this latter is less common (approximately 35% due to the use of intravascular devices).

among the given options lung cancer is the best choice as it is the most common.